Description
Lypholized powder needing reconstitution
PE-22-28 (Mini-Spadin) is a synthetic heptapeptide (7 amino acids) studied for its potential to improve mood and cognition. It works by inhibiting the TREK-1 potassium channel, which rapidly increases serotonin availability and stimulates neurogenesis.
How it Works
Unlike traditional antidepressants, which slow the reuptake of serotonin, PE-22-28 works upstream by inhibiting TREK-1 to naturally increase how much serotonin is released. This mechanism avoids common side effects associated with SSRIs and can begin working much faster in preclinical models.
Key Benefits
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- Mood Support: Researched for its rapid-onset, antidepressant-like effects and potential to help with stress and anxiety management.
- Neurogenesis: Promotes the creation of new neurons and synaptic connections (synaptogenesis) in the hippocampus.
- Cognition: Enhances mental clarity and focus, primarily as a downstream effect of mood improvement.
- Recovery: Investigated in animal models for its potential role in accelerating post-stroke recovery and battling neurodegenerative decline
Reviews
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