Description
CJC-1295 no DAC (often called Mod GRF 1-29) is a synthetic peptide that stimulates the pituitary gland to naturally produce Growth Hormone (GH). Unlike the DAC (Drug Affinity Complex) version, it has a short half-life (~30 minutes), which preserves the body’s natural pulsatile release rhythm.
Core Breakdown
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- Function: Acts as a Growth Hormone-Releasing Hormone (GHRH) analog to boost GH and IGF-1 levels.
- The “No DAC” Difference: Without DAC, the peptide clears the body quickly. This means it requires frequent injections (often daily or twice daily) to mimic the body’s natural hormone pulses.
- Common Stacks: It is frequently paired with GH-releasing peptides like Ipamorelin to create a synergistic release of GH, maximizing effectiveness while minimizing side effects.
- Benefits: Commonly researched for promoting lean muscle mass, fat loss, improved sleep, and cellular repair. [1]
- Side Effects: Potential mild side effects can include flushing, headaches, drowsiness, and localized injection site redness or pain. [1]
Typical Dosing and Research Protocol
Because the “no DAC” version has a short window of active release, protocols generally focus on small, consistent dosing. [1]
- Frequency: 1 to 2 times daily (often taken before bed or first thing in the morning).
- Synergy: Protocols frequently stack 100-200 mcg of CJC-1295 no DAC with an equal amount of Ipamorelin.




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